engr_neha asked: heparins role in growth which proteins are part of this group
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Written by World's Best on May 25th, 2008 with
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#1. May 26th, 2008, at 10:33 PM.
The BSP proteins exhibit multiple binding and functional properties. They bind to choline phospholipids of cauda epididymal spermatozoa at ejaculation [11, 12]. Also, these BSP proteins bind to sperm capacitation factors, namely, heparin [13] and high-density lipoproteins (HDL) [14]. Recently it has been shown that BSP proteins potentiate the capacitation of bovine epididymal sperm induced by heparin [15] and HDL [16]. The mechanism underlying the heparin-induced capacitation is unknown, but the binding of BSP proteins to the sperm membrane appears to increase the number of heparin-binding sites on the sperm surface [15–17]. Recent results suggest that the mechanism by which HDL and BSP proteins stimulate sperm capacitation involves cholesterol efflux [17].
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